TIPRL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1815

Novus Biologicals, part of Bio-Techne
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NB100-1815
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all TIPRL Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 225 and the C-terminus (residue 272) of human TIP41, TOR-signaling Pathway Regulator-like using the numbering given in entry NP_690866.1 (GeneID 261726).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TIPRL Antibody

Western Blot: TIPRL Antibody [NB100-1815]

Western Blot: TIPRL Antibody [NB100-1815]

Western Blot: TIPRL Antibody [NB100-1815] - WB and IP: Tip41 Antibody NB100-1815 -Detection of Human and Mouse Tip41 on HeLa whole cell lysate using NB100-1815. Efficiency of IP of Tip41 was much less when using NB100-1814 or another Tip41 antibody raised against a different epitope.
Immunohistochemistry-Paraffin: TIPRL Antibody [NB100-1815]

Immunohistochemistry-Paraffin: TIPRL Antibody [NB100-1815]

Immunohistochemistry-Paraffin: TIPRL Antibody [NB100-1815] - Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti- Tip41 used at a dilution of 1:200 (1ug/ml). Detection: DAB

Applications for TIPRL Antibody

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:500

Immunohistochemistry-Paraffin

1:100 - 1:500

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Epitope retrieval with Tris-EDTA pH9.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TIPRL

In Saccharomyces cerevisiae Tip41 is implicated to play a role in the TOR (target of rapamycin) pathway which regulates cell growth in response to nutrient signals. Tip 41 negatively regulates the TOR pathway by binding and inhibiting TAP42, an inhibitor of the SIT4 phosphatase. Alternate designations for Tip41 are Tip41 TOR signaling pathway regulator-like, TIPRL, MGC3794, dJ69E11.3, and RP1-69E11.1.

Alternate Names

dJ69E11.3, MGC3794, putative MAPK activating protein, Putative MAPK-activating protein PM10, TIP41, TOR signaling pathway regulator-like (S. cerevisiae), TIP41-like protein, TIP41Type 2A-interacting protein, TIPTIP41, TOR signalling pathway regulator-like (S. cerevisiae)

Entrez Gene IDs

261726 (Human); 226591 (Mouse)

Gene Symbol

TIPRL

UniProt

NP_690866.1 (Human)

Additional TIPRL Products

Product Documents for TIPRL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TIPRL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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