TIPRL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-51995

Novus Biologicals, part of Bio-Techne
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NBP1-51995
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all TIPRL Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RIDPNPADSQKSTQ corresponding to C-Terminus according to NP_690866.1.

Epitope

C-RIDPNPADSQKSTQ

Reactivity Notes

Expected from sequence similarity: Mouse, Rat, Canine, Bovine

Specificity

This antibody is expected to recognize isoform 1 (NP_690866.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for TIPRL Antibody

Western Blot: TIPRL Antibody [NBP1-51995]

Western Blot: TIPRL Antibody [NBP1-51995]

Western Blot: TIPRL Antibody [NBP1-51995] - (1ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: TIPRL Antibody [NBP1-51995]

Immunohistochemistry-Paraffin: TIPRL Antibody [NBP1-51995]

Immunohistochemistry-Paraffin: TIPRL Antibody [NBP1-51995] - 3.75ug/ml staining of paraffin embedded Human Breast. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for TIPRL Antibody

Application
Recommended Usage

Immunohistochemistry

1-3ug/ml

Peptide ELISA

Detection limit 1:16000

Western Blot

1:1000
Application Notes
Western blot: Approx 30kDa band observed in lysates of cell line K562 (calculated MW of 31.4kDa according to NP_690866.1). Primary incubation was 1 hour
IHC: Paraffin embedded Human Breast.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TIPRL

TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 300141) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM]

Alternate Names

dJ69E11.3, MGC3794, putative MAPK activating protein, Putative MAPK-activating protein PM10, TIP41, TOR signaling pathway regulator-like (S. cerevisiae), TIP41-like protein, TIP41Type 2A-interacting protein, TIPTIP41, TOR signalling pathway regulator-like (S. cerevisiae)

Entrez Gene IDs

261726 (Human); 226591 (Mouse); 360869 (Rat)

Gene Symbol

TIPRL

UniProt

NP_690866.1 (Human)

Additional TIPRL Products

Product Documents for TIPRL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TIPRL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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