TMC1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11011

Novus Biologicals, part of Bio-Techne
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NBP3-11011-100ul
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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all TMC1 Antibodies »

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of mouse TMC1 (NP_083229.1). Peptide sequence RDVINEDDPEPEPEDEETRKAREKERRRRLRRGAEEEEEIDEEELERLKA

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

83 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TMC1 Antibody

Western Blot: TMC1 Antibody [NBP3-11011]

Western Blot: TMC1 Antibody [NBP3-11011]

Western Blot: TMC1 Antibody [NBP3-11011] - Western blot analysis of TMC1 in Mouse MEF Whole Cell lysates. Antibody dilution at 1ug/ml

Applications for TMC1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMC1

The TMC1 gene codes a 760 amino acid long, 87 kDA transmembrane channel-like protein 1 that is critical for the function of cochlear hair cells. The specific role of this gene, however, is unknown. This gene is known to interact with genes PRKAA1, MAP1LC3B, GABARAPL2, and NSMAF. Defects in the TMC1 gene cause deafness autosomal dominant type 36 and type 7. Additionally, it has been linked to nonsyndromic deafness, hearing loss, sensorineural hearing loss, megacolon, and enlarged vestibular aqueducts.

Alternate Names

DFNA36, DFNB11, DFNB7, transmembrane channel-like 1, transmembrane channel-like protein 1, Transmembrane cochlear-expressed protein 1, transmembrane, cochlear expressed, 1

Gene Symbol

TMC1

Additional TMC1 Products

Product Documents for TMC1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TMC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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