TMEFF2/Tomoregulin-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84362

Novus Biologicals, part of Bio-Techne
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NBP1-84362
NBP1-84362-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TMEFF2/Tomoregulin-2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMEFF2/Tomoregulin-2 Antibody

Western Blot: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Western Blot: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Western Blot: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362] - Analysis in human cell line U-87 MG.
Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362] - Staining of human prostate shows weak granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362] - Staining of human prostate shows moderate cytoplasmic positivity in glandular cells.
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Applications for TMEFF2/Tomoregulin-2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEFF2/Tomoregulin-2

TMEFF2(transmembrane protein with EGF-like and two follistatin-like domains 2), a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor-like domain, had limited normal tissue distribution and was highly overexpressed in prostate cancer. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. Down-regulated in tumor cell lines in response to a high level of methylation in the 5' region. Clone J4B6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TMEFF2 protein.

Long Name

Transmembrane Protein with EFG-like and two Follistatin-like Domains

Alternate Names

TENB2, Tomoregulin-2, Tomoregulin2

Gene Symbol

TMEFF2

Additional TMEFF2/Tomoregulin-2 Products

Product Documents for TMEFF2/Tomoregulin-2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMEFF2/Tomoregulin-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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