TMEM18 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90558

Novus Biologicals, part of Bio-Techne
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NBP1-90558
NBP1-90558-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TMEM18 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MPSAFSVSSFPVSIPAVLTQTDWTEP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMEM18 Antibody

Immunocytochemistry/ Immunofluorescence: TMEM18 Antibody [NBP1-90558]

Immunocytochemistry/ Immunofluorescence: TMEM18 Antibody [NBP1-90558]

Immunocytochemistry/Immunofluorescence: TMEM18 Antibody [NBP1-90558] - Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.
Immunohistochemistry: TMEM18 Antibody [NBP1-90558]

Immunohistochemistry: TMEM18 Antibody [NBP1-90558]

Immunohistochemistry: TMEM18 Antibody [NBP1-90558] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine pancreas.

Applications for TMEM18 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEM18

TMEM18 is an obesity risk gene. It is a small protein of 140 residues and is predicted to be mostly alpha-helical with three transmembrane parts. TMEM18 forms homooligomers, independently of the DNA-binding domain. TMEM18 localizes to the nuclear membrane and binds to DNA in a sequence-specific manner. TMEM18 is a transcription repressor sequence-specific ssDNA and dsDNA binding protein with preference for GCT end CTG repeats. TMEM18 is a cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).

Long Name

Transmembrane Protein 18

Alternate Names

transmembrane protein 18

Gene Symbol

TMEM18

Additional TMEM18 Products

Product Documents for TMEM18 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMEM18 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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