TMEM43 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84132

Novus Biologicals, part of Bio-Techne
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NBP1-84132
NBP1-84132-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (92%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Proximity Ligation Assay, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TMEM43 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FKSLSLSKLEDPHVDIIRRGDFFYHSENPKYPEVGDLRVSFSYAGLSGDDPDLGPAHVVTVIARQRGDQLVPFSTKSGDTLLLLHHGDFSAEEVFHRELRSNSMKT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMEM43 Antibody

Immunohistochemistry-Paraffin: TMEM43 Antibody [NBP1-84132]

Immunohistochemistry-Paraffin: TMEM43 Antibody [NBP1-84132]

Immunohistochemistry-Paraffin: TMEM43 Antibody [NBP1-84132] - Staining of human skin shows moderate to strong positivity in nuclear membrane in keratinocytes.
Immunohistochemistry-Paraffin: TMEM43 Antibody [NBP1-84132]

Immunohistochemistry-Paraffin: TMEM43 Antibody [NBP1-84132]

Immunohistochemistry-Paraffin: TMEM43 Antibody [NBP1-84132] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: TMEM43 Antibody [NBP1-84132]

Immunohistochemistry-Paraffin: TMEM43 Antibody [NBP1-84132]

Immunohistochemistry-Paraffin: TMEM43 Antibody [NBP1-84132] - Staining of human prostate shows weak positivity in nuclear membrane in glandular cells, as well as in smooth muscle cells.

Applications for TMEM43 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEM43

TMEM43 belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq].

Alternate Names

ARVC5, ARVD5, DKFZp586G1919, LUMA, MGC3222, Protein LUMA, transmembrane protein 43

Gene Symbol

TMEM43

Additional TMEM43 Products

Product Documents for TMEM43 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMEM43 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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