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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TMEM88. The immunogen is located within amino acids 110 - 160 of TMEM88. Amino Acid Squence: LVPYSRALYRRRAPQPR

Specificity

At least two isoforms of TMEM88 are known to exist; this antibody will recognize both isoforms.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMEM88 Antibody - BSA Free

Western Blot: TMEM88 AntibodyBSA Free [NBP1-76591]

Western Blot: TMEM88 AntibodyBSA Free [NBP1-76591]

Western Blot: TMEM88 Antibody [NBP1-76591] - Human brain tissue lysate with TMEM88 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
TMEM88 Antibody - BSA Free

Immunohistochemistry: TMEM88 Antibody - BSA Free [NBP1-76591] -

Immunohistochemistry: TMEM88 Antibody - BSA Free [NBP1-76591] - Immunohistochemistry of TMEM88 in mouse brain tissue with TMEM88 antibody at 2.5 ug/mL.
TMEM88 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: TMEM88 Antibody - BSA Free [NBP1-76591] -

Immunocytochemistry/ Immunofluorescence: TMEM88 Antibody - BSA Free [NBP1-76591] - Immunofluorescence of TMEM88 in mouse brain tissue with TMEM88 antibody at 20 ug/mL.

Applications for TMEM88 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEM88

Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.

Long Name

Transmembrane Protein 88

Alternate Names

TMEM88A

Gene Symbol

TMEM88

Additional TMEM88 Products

Product Documents for TMEM88 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TMEM88 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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