TMPRSS3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-77342

Novus Biologicals, part of Bio-Techne
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NB100-77342
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all TMPRSS3 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EKIVYHSKYKPKR corresponding to internal region according to NP_076927.1, NP_115777.1, NP_115780.1, NP_115781.1.

Epitope

EKIVYHSKYKPKR

Specificity

This antibody is expected to recognise all four reported isoforms (NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1)

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for TMPRSS3 Antibody

Western Blot: TMPRSS3 Antibody [NB100-77342]

Western Blot: TMPRSS3 Antibody [NB100-77342]

Western Blot: TMPRSS3 Antibody [NB100-77342] - (0.1ug/ml) staining of A431 cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for TMPRSS3 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 48 kDa band observed in A431 lysates (calculated MW of 49.4 kDa band according to NP_076927.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TMPRSS3

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Four alternatively spliced variants have been described, two of which encode identical products.

Long Name

TransmembraneSerine Protease 3

Alternate Names

DFNB10, DFNB8, ECHOS1, TADG12

Entrez Gene IDs

64699 (Human); 140765 (Mouse)

Gene Symbol

TMPRSS3

UniProt

NP_076927.1 (Human)

Additional TMPRSS3 Products

Product Documents for TMPRSS3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMPRSS3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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