TNF RI/TNFRSF1A Antibody (001)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89687

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-89687-100ul
NBP2-89687-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 001

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TNF RI/TNFRSF1A Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human TNF RI/TNFRSF1A (Accession#: NP_001056.1; Met1-Thr211).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for TNF RI/TNFRSF1A Antibody (001)

Immunocytochemistry/ Immunofluorescence: TNF RI/TNFRSF1A Antibody (001) [NBP2-89687]

Immunocytochemistry/ Immunofluorescence: TNF RI/TNFRSF1A Antibody (001) [NBP2-89687]

Immunocytochemistry/Immunofluorescence: TNF RI/TNFRSF1A Antibody (001) [NBP2-89687] - Staining of Human TNFRI in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human TNFRI monoclonal antibody (1:60) at 4c overnight. Then cells were stained with the Alexa Fluor(R) 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.

Applications for TNF RI/TNFRSF1A Antibody (001)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:20-1:100
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TNF RI/TNFRSF1A

The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Long Name

Tumor Necrosis Factor Receptor I

Alternate Names

CD120a, TNFRI, TNFRSF1A

Gene Symbol

TNFRSF1A

Additional TNF RI/TNFRSF1A Products

Product Documents for TNF RI/TNFRSF1A Antibody (001)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TNF RI/TNFRSF1A Antibody (001)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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