TOPORS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-39060

Novus Biologicals, part of Bio-Techne
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NBP2-39060
NBP2-39060-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TOPORS Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: IVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDETPGPSYSSSEQVHVTMSSLL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TOPORS Antibody

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060] - Staining in human testis and pancreas tissues using anti-TOPORS antibody. Corresponding TOPORS RNA-seq data are presented for the same tissues.

Applications for TOPORS Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TOPORS

TOPORS functions as an ubiquitin-protein E3 ligase and as an E3 SUMO1-protein ligase. Can both ubiquitinate and sumoylate p53

Alternate Names

EC 6.3.2.-, LUNtopoisomerase I binding, arginine/serine-rich, p53-binding protein 3, P53BP3, retinitis pigmentosa 31 (autosomal dominant), RP31, SUMO1-protein E3 ligase Topors, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, Topoisomerase I-binding arginine/serine-rich protein, Topoisomerase I-binding RING finger protein, TP53BPLE3 ubiquitin-protein ligase Topors, Tumor suppressor p53-binding protein 3

Gene Symbol

TOPORS

UniProt

Q9NS56 (Human)

Additional TOPORS Products

Product Documents for TOPORS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TOPORS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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