TORC3/CRTC3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83615

Novus Biologicals, part of Bio-Techne
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NBP1-83615
NBP1-83615-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TORC3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HGLVERPSRNRFHPLHRRSGDKPGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TORC3/CRTC3 Antibody

Immunocytochemistry/ Immunofluorescence: TORC3/CRTC3 Antibody [NBP1-83615]

Immunocytochemistry/ Immunofluorescence: TORC3/CRTC3 Antibody [NBP1-83615]

Immunocytochemistry/Immunofluorescence: TORC3/CRTC3 Antibody [NBP1-83615] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
Immunohistochemistry-Paraffin: TORC3/CRTC3 Antibody [NBP1-83615]

Immunohistochemistry-Paraffin: TORC3/CRTC3 Antibody [NBP1-83615]

Immunohistochemistry-Paraffin: TORC3/CRTC3 Antibody [NBP1-83615] - Staining of human liver shows strong cytoplasmic, membranous and nuclear positivity in hepatocytes.

Applications for TORC3/CRTC3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TORC3

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMPresponse element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active whendephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 withTAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potentcoactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activationof the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)

Long Name

Transducer of Regulated CREB-binding Protein 3

Alternate Names

CRTC3

Gene Symbol

CRTC3

Additional TORC3 Products

Product Documents for TORC3/CRTC3 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TORC3/CRTC3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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