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TOX Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87857

Novus Biologicals, part of Bio-Techne
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NBP1-87857
NBP1-87857-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant TOX Protein corresponding to amino acids: PDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPGPSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQN

Reactivity Notes

Reactivity reported in scientific literature (PMID: 24304814)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TOX Antibody

Immunohistochemistry-Paraffin: TOX Antibody [NBP1-87857]

Immunohistochemistry-Paraffin: TOX Antibody [NBP1-87857]

Immunohistochemistry-Paraffin: TOX Antibody [NBP1-87857] - Staining in human tonsil and liver tissues. Corresponding TOX RNA-seq data are presented for the same tissues.
Western Blot: TOX Antibody [NBP1-87857]

Western Blot: TOX Antibody [NBP1-87857]

Western Blot: TOX Antibody [NBP1-87857] - Analysis in human cell line MOLT-4.
Immunohistochemistry-Paraffin: TOX Antibody [NBP1-87857]

Immunohistochemistry-Paraffin: TOX Antibody [NBP1-87857]

Immunohistochemistry-Paraffin: TOX Antibody [NBP1-87857] - Staining of human tonsil shows strong nuclear positivity in germinal center cells and a subset of non-germinal center cells.

Applications for TOX Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TOX

The protein encoded by the thymocyte selection-associated high mobility group box gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.

Long Name

Thymocyte Selection Associated High Mobility Group Box

Alternate Names

KIAA0808, TOX1

Gene Symbol

TOX

Additional TOX Products

Product Documents for TOX Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TOX Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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