TPT1/TCTP Antibody (3C7)

Novus Biologicals, part of Bio-Techne | Catalog # H00007178-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3C7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TPT1/TCTP Antibodies »

Product Specifications

Immunogen

TPT1 (AAH22436, 35 a.a. ~ 138 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC

Specificity

TPT1 - tumor protein, translationally-controlled 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for TPT1/TCTP Antibody (3C7)

Western Blot: TPT1/TCTP Antibody (3C7) [H00007178-M01]

Western Blot: TPT1/TCTP Antibody (3C7) [H00007178-M01]

Western Blot: TPT1/TCTP Antibody (3C7) [H00007178-M01] - TPT1 monoclonal antibody (M01), clone 3C7 Analysis of TPT1 expression in HepG2.
Immunocytochemistry/ Immunofluorescence: TPT1/TCTP Antibody (3C7) [H00007178-M01]

Immunocytochemistry/ Immunofluorescence: TPT1/TCTP Antibody (3C7) [H00007178-M01]

Immunocytochemistry/Immunofluorescence: TPT1/TCTP Antibody (3C7) [H00007178-M01] - Analysis of monoclonal antibody to TPT1 on HeLa cell. Antibody concentration 30 ug/ml.
ELISA: TPT1/TCTP Antibody (3C7) [H00007178-M01]

ELISA: TPT1/TCTP Antibody (3C7) [H00007178-M01]

ELISA: TPT1/TCTP Antibody (3C7) [H00007178-M01] - Detection limit for recombinant GST tagged TPT1 is approximately 0.3ng/ml as a capture antibody.

Applications for TPT1/TCTP Antibody (3C7)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TPT1/TCTP

Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family and is detected as a protein of 21 kDa in mice and 23 kDa in human. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down Syndrome.

Long Name

Translationally-controlled Tumor Protein 1

Alternate Names

Fortilin, HRF, p02, TCTP

Entrez Gene IDs

7178 (Human)

Gene Symbol

TPT1

OMIM

600763 (Human)

UniProt

AAH22436 (Human)

Additional TPT1/TCTP Products

Product Documents for TPT1/TCTP Antibody (3C7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TPT1/TCTP Antibody (3C7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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