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TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90118

Novus Biologicals, part of Bio-Techne
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NBP1-90118
NBP1-90118-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AFEHYVNHRKHNIPHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody

Immunocytochemistry/ Immunofluorescence: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NBP1-90118]

Immunocytochemistry/ Immunofluorescence: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NBP1-90118]

Immunocytochemistry/Immunofluorescence: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NBP1-90118] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
Immunohistochemistry-Paraffin: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NBP1-90118]

Immunohistochemistry-Paraffin: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NBP1-90118]

Immunohistochemistry-Paraffin: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NBP1-90118] - Staining of human cerebral cortex shows cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NBP1-90118]

Immunohistochemistry-Paraffin: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NBP1-90118]

Immunohistochemistry-Paraffin: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NBP1-90118] - Staining of human tonsil shows distinct positivity in the reaction centra.

Applications for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TR alpha/NR1A1

Thyroid Hormone Receptor alpha is encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Long Name

Thyroid Hormone Receptor alpha

Alternate Names

NR1A1, THRA, v-ErbA1

Gene Symbol

THRA

Additional TR alpha/NR1A1 Products

Product Documents for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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