TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57253

Novus Biologicals, part of Bio-Techne
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NBP2-57253
NBP2-57253-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TR beta 1/NR1A2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: MTPNSMTENGLTAWDKPKHCPDREHDWKLVGMSEACLHRKSHSERRSTLK

Reactivity Notes

Mouse 82%, Rat 82%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody

Immunocytochemistry/ Immunofluorescence: TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody [NBP2-57253]

Immunocytochemistry/ Immunofluorescence: TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody [NBP2-57253]

Immunocytochemistry/Immunofluorescence: TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody [NBP2-57253] - Staining of human cell line SiHa shows localization to nuclear bodies.

Applications for TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TR beta 1/NR1A2

Thyroid Hormone Receptor beta is encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Defects in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH).

Long Name

Thyroid Hormone Receptor beta 1

Alternate Names

NR1A2, THRB, v-ErbA2

Gene Symbol

THRB

Additional TR beta 1/NR1A2 Products

Product Documents for TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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