TR4/NR2C2 Antibody (SR2096)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22644

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22644-100ul
NBP3-22644-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2096

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TR4/NR2C2 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human TR4/NR2C2 (Uniprot #: P49116)

Specificity

Detects endogenous levels of total TR4/NR2C2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TR4/NR2C2 Antibody (SR2096)

Western Blot: TR4/NR2C2 Antibody (SR2096) [NBP3-22644] -

Western Blot: TR4/NR2C2 Antibody (SR2096) [NBP3-22644] - Western blot analysis using NBP3-22644 in PC-3 cell lysate.

Applications for TR4/NR2C2 Antibody (SR2096)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TR4/NR2C2

TR4 (TAK1, NR2C2) is an orphan nuclear receptor. TR4 was originally cloned from lymphoblastoma Raji cells or mouse brain cDNA library. No ligand has been reported. Northern blot shows TR4 is transcribed as a 9kb mRNA in many tissues and as a 2.8kb mRNA in testis, mainly in spermatocytes. TR4 has two isoforms called TR4alpha1 and TR4 alpha2,which differ in 19 amino acids coded by two separate exons. Both products translated from the 9kb transcript are ubiquitously expressed. Since TR4 binds to the same elements for the RAR-RXR or TR-RXR heterodimers, TR4 may have an inhibitory effect for retinoic-acid mediated transactivation.

Long Name

Testicular Orphan Nuclear Receptor 4

Alternate Names

NR2C2, TAK1

Gene Symbol

NR2C2

Additional TR4/NR2C2 Products

Product Documents for TR4/NR2C2 Antibody (SR2096)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TR4/NR2C2 Antibody (SR2096)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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