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TRAF-1 Antibody (TRAF1/3365) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27024

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # TRAF1/3365

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Recombinant fragment of human TRAF-1 protein (around aa 73-219) (exact sequence is proprietary)

Localization

Cytoplasm

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.

Scientific Data Images for TRAF-1 Antibody (TRAF1/3365) - Azide and BSA Free

TRAF-1 Antibody (TRAF1/3365)

Protein Array: TRAF-1 Antibody (TRAF1/3365) - Azide and BSA Free [NBP3-27024] -

Analysis of Protein Array containing more than 19,000 full-length human proteins using TRAF-1 Antibody (TRAF1/3365) - Azide and BSA Free

Applications for TRAF-1 Antibody (TRAF1/3365) - Azide and BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
ELISA: For coating, order antibody without BSA. Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: TRAF-1

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis. This antibody recognizes TRAF1; human TRAF1 is a 416 amino acid protein.

Long Name

TNF Receptor-Associated Factor 1

Alternate Names

EBI6, TRAF1

Gene Symbol

TRAF1

Additional TRAF-1 Products

Product Documents for TRAF-1 Antibody (TRAF1/3365) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TRAF-1 Antibody (TRAF1/3365) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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