TRAF-2 Antibody (5C2C3) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61661

Novus Biologicals, part of Bio-Techne
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NBP2-61661
NBP2-61661-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 5C2C3

Format

BSA Free

Concentration

1 mg/ml

View all TRAF-2 Antibodies »

Product Summary for TRAF-2 Antibody (5C2C3) - BSA Free

Immunogen

Purified recombinant fragment of human TRAF-2 (AA: 39-188) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

55.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TRAF-2 Antibody (5C2C3) - BSA Free

Western Blot: TRAF-2 Antibody (5C2C3)BSA Free [NBP2-61661]

Western Blot: TRAF-2 Antibody (5C2C3)BSA Free [NBP2-61661]

Western Blot: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis using TRAF2 mAb against human TRAF2 (AA: 39-188) recombinant protein. (Expected MW is 42.5 kDa)
Immunocytochemistry/ Immunofluorescence: TRAF-2 Antibody (5C2C3) - BSA Free [NBP2-61661]

Immunocytochemistry/ Immunofluorescence: TRAF-2 Antibody (5C2C3) - BSA Free [NBP2-61661]

Immunocytochemistry/Immunofluorescence: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis of MCF-7 cells using TRAF2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.
Immunohistochemistry: TRAF-2 Antibody (5C2C3) - BSA Free [NBP2-61661]

Immunohistochemistry: TRAF-2 Antibody (5C2C3) - BSA Free [NBP2-61661]

Immunohistochemistry: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis of paraffin-embedded cervical cancer tissues using TRAF2 mouse mAb with DAB staining.
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Applications for TRAF-2 Antibody (5C2C3) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Immunocytochemistry/ Immunofluorescence

1:200-1:1000

Immunohistochemistry

1:200-1:1000

Immunohistochemistry-Paraffin

1:200-1:1000

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAF-2

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.;

Long Name

TNF Receptor-Associated Factor 2

Alternate Names

TRAF2, TRAP3

Gene Symbol

TRAF2

Additional TRAF-2 Products

Product Documents for TRAF-2 Antibody (5C2C3) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TRAF-2 Antibody (5C2C3) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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