TRAF-4 Antibody (SR1969)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21648

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21648-100ul
NBP3-21648-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1969

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRAF-4 Antibodies »

Product Summary for TRAF-4 Antibody (SR1969)

Immunogen

A synthesized peptide derived from human TRAF-4 (Uniprot #: Q9BUZ4)

Specificity

Detects endogenous levels of total TRAF-4

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TRAF-4 Antibody (SR1969)

Western Blot: TRAF-4 Antibody (SR1969) [NBP3-21648] -

Western Blot: TRAF-4 Antibody (SR1969) [NBP3-21648] - Western blot analysis using NBP3-21648 in HeLa cell lysate.

Applications for TRAF-4 Antibody (SR1969)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:1000-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAF-4

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.

Long Name

TNF Receptor-Associated Factor 4

Alternate Names

CART1, MLN62, TRAF4

Gene Symbol

TRAF4

Additional TRAF-4 Products

Product Documents for TRAF-4 Antibody (SR1969)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TRAF-4 Antibody (SR1969)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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