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TRAF-6 Antibody (S09-3F4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19793

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-19793-100ul
NBP3-19793-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S09-3F4

Concentration

0.3 mg/ml

Product Summary for TRAF-6 Antibody (S09-3F4)

Immunogen

A synthetic peptide of human TRAF-6 (Uniprot # Q9Y4K3)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TRAF-6 Antibody (S09-3F4)

Western Blot: TRAF-6 Antibody (S09-3F4) [NBP3-19793]

Western Blot: TRAF-6 Antibody (S09-3F4) [NBP3-19793]

Western Blot: TRAF-6 Antibody (S09-3F4) [NBP3-19793] - Western blot detection of TRAF-6 in 293 cell lysates using NBP3-19793 (1:1000 diluted). Predicted band size: 60KDa. Observed band size: 60KDa.

Applications for TRAF-6 Antibody (S09-3F4)

Application
Recommended Usage

Western Blot

1/1000-1/5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAF-6

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.

Long Name

TNF Receptor-Associated Factor 6

Alternate Names

TRAF6

Gene Symbol

TRAF6

Additional TRAF-6 Products

Product Documents for TRAF-6 Antibody (S09-3F4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TRAF-6 Antibody (S09-3F4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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