TRAILR2/TNFRSF10B Antibody (drozitumab) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28785B

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Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP3-28785

Alexa Fluor 350

NBP3-28785AF350

Alexa Fluor 405

NBP3-28785AF405

Alexa Fluor 488

NBP3-28785AF488

Alexa Fluor 532

NBP3-28785AF532

Alexa Fluor 594

NBP3-28785AF594

Alexa Fluor 647

NBP3-28785AF647

Alexa Fluor 700

NBP3-28785AF700

Alexa Fluor 750

NBP3-28785AF750

Allophycocyanin

NBP3-28785APC

CoraFluor 1

NBP3-28785CL1

DyLight 350

NBP3-28785UV

DyLight 405

NBP3-28785V

DyLight 488

NBP3-28785G

DyLight 550

NBP3-28785R

DyLight 594

NBP3-28785DL594

DyLight 650

NBP3-28785C

DyLight 680

NBP3-28785FR

DyLight 755

NBP3-28785IR

FITC

NBP3-28785F

HRP

NBP3-28785H

Janelia Fluor 525

NBP3-28785JF525

Janelia Fluor 549

NBP3-28785JF549

Janelia Fluor 646

NBP3-28785JF646

Janelia Fluor 669

NBP3-28785JF669

mFluor Violet 450 SE

NBP3-28785MFV450

mFluor Violet 500 SE

NBP3-28785MFV500

mFluor Violet 610 SE

NBP3-28785MFV610

PE

NBP3-28785PE

PerCP

NBP3-28785PCP

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Biotin

Antibody Source

Recombinant Monoclonal Human IgG₁ Clone # drozitumab

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRAIL R2/TNFRSF10B Antibodies »

Product Specifications

Immunogen

TNFRSF10B / TRAILR2 / CD262

Clonality

Monoclonal

Host

Human

Isotype

IgG₁

Applications for TRAILR2/TNFRSF10B Antibody (drozitumab) [Biotin]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TRAIL R2/TNFRSF10B

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently (1-2). Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB.

Long Name

TRAIL Receptor 2

Alternate Names

CD262, DR5, TNFRSF10B, TRAILR2

Gene Symbol

TNFRSF10B

Additional TRAIL R2/TNFRSF10B Products

Product Documents for TRAILR2/TNFRSF10B Antibody (drozitumab) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for TRAILR2/TNFRSF10B Antibody (drozitumab) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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