TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80071

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # TR3.06

Format

BSA Free

Concentration

1 mg/ml

View all TRAIL R3/TNFRSF10C Antibodies »

Product Summary for TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free

Immunogen

Recombinant human TRAILR3/TNFRSF10C (DcR1).

Specificity

Recognizes human TRAILR3/TNFRSF10C. Does not cross-react with human TRAIL-R1, -R2 or -R4.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free

Immunohistochemistry-Paraffin: TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free [NBP2-80071]

Immunohistochemistry-Paraffin: TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free [NBP2-80071]

Immunohistochemistry-Paraffin: TRAILR3/TNFRSF10C Antibody (TR3.06) [NBP2-80071] - Negative control.
Immunohistochemistry-Paraffin: TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free [NBP2-80071]

Immunohistochemistry-Paraffin: TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free [NBP2-80071]

Immunohistochemistry-Paraffin: TRAILR3/TNFRSF10C Antibody (TR3.06) [NBP2-80071] - Immunohistochemistry detection of endogenous TRAIL-R3 in paraffin-embedded human carcinoma tissues (colon, tonsil) using mAb to TRAIL-R3 (TR3.06).

Applications for TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free

Application
Recommended Usage

Immunohistochemistry

20 ug/mL

Immunohistochemistry-Paraffin

20 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 10% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAIL R3/TNFRSF10C

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.

Long Name

TRAIL Receptor 3

Alternate Names

CD263, DcR1, TNFRSF10C, TRAILR3

Gene Symbol

TNFRSF10C

Additional TRAIL R3/TNFRSF10C Products

Product Documents for TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRAILR3/TNFRSF10C Antibody (TR3.06) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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