TRAIP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56180

Novus Biologicals, part of Bio-Techne
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NB100-56180
NB100-56180SS
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all TRAIP Antibodies »

Product Summary for TRAIP Antibody

Immunogen

A synthetic peptide corresponding to amino acids 294-313 (ESPAPVEVNLKLRRPSFRDD) of human TRIP was used as immunogen; GenBank no. gi|40807469|ref|NP_005870.2|.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRAIP Antibody

Immunohistochemistry-Paraffin: TRAIP Antibody [NB100-56180]

Immunohistochemistry-Paraffin: TRAIP Antibody [NB100-56180]

Immunohistochemistry-Paraffin: TRAIP Antibody - Unpurified [NB100-56180] - TRAIP was detected in immersion fixed paraffin-embedded sections of human tonsil using this antibody at 1:1000 for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC003). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Nuclear staining was observed in lymphocytes.

Applications for TRAIP Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:1000-1:5000

Immunoprecipitation

1:50-1:200

Western Blot

1:1000-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAIP

The TNF receptor-associated factor (TRAF) family is a group of cytoplasmic adapter proteins that link a wide variety of cell surface receptors including the TNF and IL-1 receptor (TRNFR and IL-1R) superfamily to diverse signaling cascades involved in differentiation, proliferation, activation and apoptosis. TRIP (TRAF-interacting protein) was identified in 1997 as a component of receptor-TRAF signaling complexes (Lee, 1997). TRIP (also known as TRAIP) has been shown to associate with TRNFR2 or CD30 signaling complexes through its interaction with TRAF proteins and inhibit TRAF2-mediated NF-kB activation (Lee, 1997; Regamey et al, 2003). The recruitment of different TRAFs and TRAF associated proteins like TRIP to receptor complexes can help regulate and provide specificity to the intracellular signals triggered by the cell surface receptors.

Alternate Names

RNF206TRIPRING finger protein 206, TRAF interacting protein, TRAF-interacting protein

Entrez Gene IDs

10293 (Human)

Gene Symbol

TRAIP

Additional TRAIP Products

Product Documents for TRAIP Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TRAIP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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