Transgelin/TAGLN/SM22 alpha Antibody (SR1369)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21936

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21936-100ul
NBP3-21936-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1369

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Transgelin/TAGLN Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Transgelin/TAGLN/SM22 alpha (Uniprot #: Q01995)

Specificity

Detects endogenous levels of total Transgelin/TAGLN/SM22 alpha

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

23 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Transgelin/TAGLN/SM22 alpha Antibody (SR1369)

Western Blot: Transgelin/TAGLN/SM22 alpha Antibody (SR1369) [NBP3-21936] -

Western Blot: Transgelin/TAGLN/SM22 alpha Antibody (SR1369) [NBP3-21936] - Western blot analysis using NBP3-21936 in Human stomach lysate.

Applications for Transgelin/TAGLN/SM22 alpha Antibody (SR1369)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Transgelin/TAGLN

In contrast to fast and slow skeletal muscle cells that fuse and terminally differentiate, smooth muscle cells are able to simultaneously proliferate and express lineage-restricted proteins. One of these proteins, expressed exclusively in smooth muscles, has been referred to as SM22-alpha, a 22 kDa protein with structural similarity to the vertebrate thin filament myofibrillar regulatory protein calponin and the Drosophila muscle protein mp20, neither of which play a direct role in the contractile apparatus.The protein is a transformation and shape-change sensitive actin cross-linking/geling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.

Alternate Names

SM22 alpha, TAGLN, WS3-10

Gene Symbol

TAGLN

Additional Transgelin/TAGLN Products

Product Documents for Transgelin/TAGLN/SM22 alpha Antibody (SR1369)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Transgelin/TAGLN/SM22 alpha Antibody (SR1369)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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