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Transglutaminase 1/TGM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25206

Novus Biologicals, part of Bio-Techne
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NBP3-25206

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein Transglutaminase 1/TGM1 using the following amino acid sequence: DLSLTLLGAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Transglutaminase 1/TGM1 Antibody

Transglutaminase 1/TGM1 Antibody Immunohistochemistry-Paraffin: Transglutaminase 1/TGM1 Antibody [NBP3-25206]

Immunohistochemistry-Paraffin: Transglutaminase 1/TGM1 Antibody [NBP3-25206]

Staining of human esophagus shows strong membranous positivity in squamous epithelial cells.

Applications for Transglutaminase 1/TGM1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Transglutaminase 1/TGM1

Tissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is one of the more common disorders in Western countries.

Alternate Names

ICR2, KTG, LI1, TGase-1, TGK, TGM1

Gene Symbol

TGM1

Additional Transglutaminase 1/TGM1 Products

Product Documents for Transglutaminase 1/TGM1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Transglutaminase 1/TGM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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