TRF-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-891

Novus Biologicals, part of Bio-Techne
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NB100-891
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all TRF-1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-TMKKLKLISSDSED corresponding to C-Terminus according to NP_003209.2, NP_059523.2.

Specificity

This antibody is expected to recognise isoform 1 (NP_059523.2) and isoform 2 (NP_003209.2).

Marker

Telomere Marker

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for TRF-1 Antibody

Western Blot: TRF-1 Antibody [NB100-891]

Western Blot: TRF-1 Antibody [NB100-891]

Western Blot: TRF-1 Antibody [NB100-891] - Analysis of TRF1 in HeLa lysate (RIPA buffer, 30ug total protein per lane) using this antibody at 2 ug/ml. Primary incubated for 12 hour. Detected using chemiluminescence.

Applications for TRF-1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 60-65 kDa band and 45 kDa band bands observed in HeLa lysate.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TRF-1

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

Long Name

Telomeric Repeat Binding Factor

Alternate Names

PIN-2, TERF1, TRF1

Entrez Gene IDs

7013 (Human)

Gene Symbol

TERF1

UniProt

NP_003209 (Human)

Additional TRF-1 Products

Product Documents for TRF-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRF-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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