TRIM Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17096

Novus Biologicals, part of Bio-Techne
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NBP3-17096-100ul
NBP3-17096-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TRIM Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: IDASVSKTTLVDSFSPESQAVEENIHDDPIRLFGLIRAKREPIN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRIM Antibody

Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096]

Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096]

Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096] - Staining of human lymph node shows high expression.
Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096]

Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096]

Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096] - Analysis in human lymph node and cerebral cortex tissues using Anti-TRAT1 antibody. Corresponding TRAT1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096]

Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096]

Immunohistochemistry-Paraffin: TRIM Antibody [NBP3-17096] - Staining of human cerebral cortex shows low expression as expected.
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Applications for TRIM Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRIM

TRIM is a 30 kD disulfide-linked protein also known as T cell receptor interacting molecule. TRIM is a type III membrane protein containing a very short extracellular domain (8 amino acids). TRIM is highly expressed in T cells with some expression also observed in NK cells. TRIM is a signaling adaptor molecule that links extracellular and intracellular signaling. The TRIM protein is phosphorylated by Src kinases and associates with the PI3K regulatory subunit alpha after phosphorylation. TRIM has also been shown to associate with TCR alpha, beta, and zeta. The TRIM-4 monoclonal antibody recognizes human TRIM and has been shown to be useful for Western blotting, intracellular staining by flow cytometry, and immunofluorescence staining.

Long Name

T Cell Receptor Interacting Molecule

Alternate Names

TCRIM, TRAT1

Gene Symbol

TRAT1

Additional TRIM Products

Product Documents for TRIM Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRIM Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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