TROP-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-05036

Novus Biologicals, part of Bio-Techne
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NBP1-05036
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all TROP-2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-HYEQPTIQIELRQN corresponding to internal region according to NP_002344.2.

Epitope

internal region

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for TROP-2 Antibody

Western Blot: TROP-2 Antibody [NBP1-05036]

Western Blot: TROP-2 Antibody [NBP1-05036]

Western Blot: TROP-2 Antibody [NBP1-05036] - (0.2ug/ml) staining of Human Prostate lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: TROP-2 Antibody [NBP1-05036]

Immunohistochemistry-Paraffin: TROP-2 Antibody [NBP1-05036]

Immunohistochemistry-Paraffin: TROP-2 Antibody [NBP1-05036] - EB08839 (2.5ug/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for TROP-2 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

2.5 ug/ml

Peptide ELISA

Detection limit 1:4000

Western Blot

0.2-0.5 ug/ml
Application Notes
Western blot: Approx. 37kDa band observed in Human Prostate lysates (calculated MW of 35.7kDa according to NP_002344.2). Primary incubation was 1 hour.
IHC: Paraffin embedded Human Tonsil.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TROP-2

TROP2 encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. [provided by RefSeq]

Long Name

Tumor-associated Calcium Signal Transducer 2

Alternate Names

GA733-1, gp50, T16, TACSTD2, TROP2

Entrez Gene IDs

4070 (Human); 56753 (Mouse)

Gene Symbol

TACSTD2

UniProt

NP_002344.2

Additional TROP-2 Products

Product Documents for TROP-2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TROP-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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