Cardiac Troponin T, a 36kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.

Alternate Names

cardiac, CMD1D, CMPD2, dilated 1D (autosomal dominant), hypertrophic 2, MGC3889, RCM3, TnTc, troponin T type 2 (cardiac), troponin T, cardiac muscle

Entrez Gene IDs

7139 (Human)

Gene Symbol

TNNT2

UniProt

P45379

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Product Specific Notices for Troponin T Type 2 (cardiac) Antibody (2F3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Troponin T Type 2 (cardiac) Antibody (2F3)

Novus Biologicals, part of Bio-Techne | Catalog # NB120-10216

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Background: Troponin T Type 2 (cardiac)