Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # TT44 (BGN/1288/44)

Concentration

1.0 mg/ml

View all Troponin T Type 2 (cardiac) Antibodies »

Product Specifications

Immunogen

HMW conjugate (FMPNLVPPKIC)

Epitope

F-M-P-N-L-V-P-P-K-I-C

Localization

Cytoplasmic

Specificity

NB100-66490 recognises Troponin T Type 2 (cardiac) isoform 1. In Western blotting, this reacts with reduced purified cardiac isoform, but does not react with the skeletal isoform.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Troponin T Type 2 (cardiac) Antibody (TT44 (BGN/1288/44))

Western Blot: Troponin T Type 2 (cardiac) Antibody (BGN/1288/44)BSA Free [NB100-66490]

Western Blot: Troponin T Type 2 (cardiac) Antibody (BGN/1288/44)BSA Free [NB100-66490]

Western Blot: Troponin T Type 2 (cardiac) Antibody (BGN/1288/44) [NB100-66490] - Human Heart lysate probed with MOUSE ANTI TROPONIN T CARDIAC ISOFORM 1

Applications for Troponin T Type 2 (cardiac) Antibody (TT44 (BGN/1288/44))

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:250

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Troponin T Type 2 (cardiac)

Cardiac Troponin T, a 36kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.

Alternate Names

cardiac, CMD1D, CMPD2, dilated 1D (autosomal dominant), hypertrophic 2, MGC3889, RCM3, TnTc, troponin T type 2 (cardiac), troponin T, cardiac muscle

Entrez Gene IDs

7139 (Human)

Gene Symbol

TNNT2

UniProt

P45379

Additional Troponin T Type 2 (cardiac) Products

Product Documents for Troponin T Type 2 (cardiac) Antibody (TT44 (BGN/1288/44))

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Troponin T Type 2 (cardiac) Antibody (TT44 (BGN/1288/44))

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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