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TRPA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-98841

Novus Biologicals, part of Bio-Techne
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NB100-98841
NB100-98841-0.025ml

Key Product Details

Species Reactivity

Validated:

Mouse, Rat, Guinea Pig

Cited:

Mouse, Guinea Pig

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Product Specifications

Immunogen

A synthetic peptide from rat TRPA1 conjugated to blue carrier protein was used as the antigen.

Reactivity Notes

Guinea pig data from customer review. Mouse reactivity reported in scientific literature (PMID: 27720932).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRPA1 Antibody

Immunocytochemistry/ Immunofluorescence: TRPA1 Antibody [NB100-98841]

Immunocytochemistry/ Immunofluorescence: TRPA1 Antibody [NB100-98841]

Immunocytochemistry/Immunofluorescence: TRPA1 Antibody [NB100-98841] - IF on vagal nodose ganglia. Image from verified customer review.

Applications for TRPA1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry

1:1000

Immunohistochemistry-Paraffin

1:1000

Western Blot

1:1000
Application Notes
IF data from customer review.

Reviewed Applications

Read 1 review rated 4 using NB100-98841 in the following applications:

Formulation, Preparation, and Storage

Purification

Unpurified

Reconstitution

Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the sample size is provided in reconstituted format.

Formulation

Lyophilized from whole antisera

Preservative

No Preservative

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRPA1

The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. TISSUE SPECIFICITY: Expressed in inner ear. In inner ear, it is found in the distal half of stereocilia, along the length of the kinocilium and at high level in the pericuticular zone (at protein level). Specifically expressed in a subset of nociceptive neurons. Expressed in the same neurons that TRPV1. In contrast, it is not expressed in neurons expressing TRPM8. Expressed in the superior cervical ganglion. DEVELOPMENTAL STAGE: During utricle development, it is first expressed at E15 and E16 and peaks at E17. It drops at E18 but increases again at E19, possibly corresponding to a second wave of hair cells that are generated at E15. Inhibited by ruthenium red, a potent blocker of TRPV channels.

Long Name

Transient receptor potential cation channel subfamily A member 1

Alternate Names

ANKTM1, Wasabi receptor

Entrez Gene IDs

277328 (Mouse); 312896 (Rat)

Gene Symbol

TRPA1

Additional TRPA1 Products

Product Documents for TRPA1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TRPA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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