TRPC1 Antibody (SR1100)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22029

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22029-100ul
NBP3-22029-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1100

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRPC1 Antibodies »

Product Summary for TRPC1 Antibody (SR1100)

Immunogen

A synthesized peptide derived from human TRPC1 (Uniprot #: P48995)

Specificity

Detects endogenous levels of total TRPC1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TRPC1 Antibody (SR1100)

Western Blot: TRPC1 Antibody (SR1100) [NBP3-22029] -

Western Blot: TRPC1 Antibody (SR1100) [NBP3-22029] - Western blot analysis using NBP3-22029 in HepG2 cell lysate.

Applications for TRPC1 Antibody (SR1100)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRPC1

The TRP1 (TRPC1) gene encodes for a short transient receptor potential channel 1 protein which creates non-selective channels permeable to calcium and other cations. The long isoform is 793 amino acids long at around 91 kDA while the short isoform is 759 amino acids at approximately 87 kDA. These proteins are believed to be operated by a phosphatidylinositol messenger system. The TRP1 gene interacts with MX1, CAV1, ITPR3, HOMER1, and BMPR2 genes in pathways for CREB transcription, intracellular calcium signaling, developmental biology and pancreatic secretion. The TRP1 gene has been studied in various diseases such as kidney disease, breast cancer, neuroblastoma, prostatius, retinitis, basal cell carcinoma, muscular dystrophy, gingivitis, hypoxia, cerebritis, neurodegeneration, pyloric stenosis, and bipolar disorder.

Long Name

Short transient receptor potential channel 1

Alternate Names

TRP-1, TRP1

Gene Symbol

TRPC1

Additional TRPC1 Products

Product Documents for TRPC1 Antibody (SR1100)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRPC1 Antibody (SR1100)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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