Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TRPC3 Antibodies »

Product Specifications

Immunogen

TRPC3 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human TRPC3. The immunogen is located within amino acids 710 - 760 of TRPC3. Amino Acid Squence: RRRRLQKDIEMGMGNSKS

Specificity

TRPC3 antibody is human, mouse and rat reactive. At least four isoforms are known to exist; this antibody will detect the three largest isoforms. TRPC3 antibody is predicted to not cross-react with TRPC6.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

93 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TRPC3 Antibody - BSA Free

Western Blot: TRPC3 AntibodyBSA Free [NBP2-82043]

Western Blot: TRPC3 AntibodyBSA Free [NBP2-82043]

Western Blot: TRPC3 Antibody [NBP2-82043] - Western blot analysis of TRPC3 in human cerebellum tissue lysate with TRPC3 antibody at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry: TRPC3 Antibody - BSA Free [NBP2-82043]

Immunohistochemistry: TRPC3 Antibody - BSA Free [NBP2-82043]

Immunohistochemistry: TRPC3 Antibody [NBP2-82043] - Immunohistochemistry of TRPC3 in human brain tissue with TRPC3 antibody at 2.5 ug/mL.

Applications for TRPC3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRPC3

The transient receptor potential canonical (TRPC) group of channels, including TPRC3, is a family of receptor-activated non-selective calcium permeant cation channels. In vitro TRPC proteins can form hetero- or homo-oligomeric channels. Endogenous TRPC1, TRPC3 and TRPC7 participate in forming heteromeric store-operated channels, while TRPC3 and TRPC7 can also participate in forming heteromeric receptor-operated channels. TRPC3 plays important roles in neuronal differentiation and immune cell maturation by mediating the cationic current in response to phospholipase C activation, Ca(2+) depletion, and diacylglycerol stimulation. TRPC3 channels are highly expressed in pontine neurons and mediate a nonselective cation current in response to the neurotrophin receptor, TrkB.

Long Name

Short transient receptor potential channel 3

Alternate Names

hTrp-3, hTrp3, TRP-3, TRP3

Gene Symbol

TRPC3

Additional TRPC3 Products

Product Documents for TRPC3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TRPC3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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