TRPM2 Antibody [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NB110-81601F

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB110-81601AF350

Alexa Fluor 405

NB110-81601AF405

Alexa Fluor 488

NB110-81601AF488

Alexa Fluor 532

NB110-81601AF532

Alexa Fluor 594

NB110-81601AF594

Alexa Fluor 647

NB110-81601AF647

Alexa Fluor 700

NB110-81601AF700

Alexa Fluor 750

NB110-81601AF750

Allophycocyanin

NB110-81601APC

Biotin

NB110-81601B

CoraFluor 1

NB110-81601CL1

DyLight 350

NB110-81601UV

DyLight 405

NB110-81601V

DyLight 488

NB110-81601G

DyLight 550

NB110-81601R

DyLight 594

NB110-81601DL594

DyLight 650

NB110-81601C

DyLight 680

NB110-81601FR

DyLight 755

NB110-81601IR

HRP

NB110-81601H

Janelia Fluor 525

NB110-81601JF525

Janelia Fluor 549

NB110-81601JF549

Janelia Fluor 585

NB110-81601JF585

Janelia Fluor 635

NB110-81601JF635

Janelia Fluor 646

NB110-81601JF646

Janelia Fluor 669

NB110-81601JF669

mFluor Violet 450 SE

NB110-81601MFV450

mFluor Violet 500 SE

NB110-81601MFV500

mFluor Violet 610 SE

NB110-81601MFV610

PE

NB110-81601PE

PerCP

NB110-81601PCP

Forumulation

Catalog #

BSA Free

NB110-81601

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRPM2 Antibodies »

Product Summary for TRPM2 Antibody [FITC]

Immunogen

Synthetic peptide made to a C-terminal portion of the rat TRPM2 protein (within residues 1430-1508). [Swiss-Prot# Q5G856]

Localization

Cell membrane.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for TRPM2 Antibody [FITC]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TRPM2

TRP7 (transient receptor protein 7 or TRPC7) is the seventh identified member of mammalian TRPC channel family which includes nonselective cation channels that mediate changes in plasma membrane cation permeability induced by stimulation of PLC (phospholipase C, the cellular integrator that receives input from GPCRs/ RTK). Major cellular function of TRPC channels is to regulate Ca2+ influx across plasma membrane induced by stimulation of these receptors by hormones, neurotransmitters, and growth factors. Localized in the cell membrane and nuclear envelope as multi-pass membrane protein, TRPC7 interacts with with MX1, RNF24, PRKG1 etc. and PRKG1 mediated TRPC7 phosphorylation at Thr-15 site negatively regulates TRPC7's activity. TRP7 has been suggested to form a receptor-activated non-selective calcium permeant cation channel and is operated by a phosphatidylinositol second messenger system activated by RTKs or GPCRs. TRP7 is activated by DAG (diacylglycerol) and also upon intracellular calcium store depletion.

Alternate Names

EC 3.6.1.13, EREG1MGC133383, Estrogen-responsive element-associated gene 1 protein, KNP3LTrpC-2, Long transient receptor potential channel 2, LTrpC2, LTRPC2TRPC7transient receptor potential cation channel subfamily M member 2, NUDT9H, NUDT9L1, transient receptor potential cation channel, subfamily M, member 2, Transient receptor potential channel 7, TrpC7

Gene Symbol

TRPM2

Additional TRPM2 Products

Product Documents for TRPM2 Antibody [FITC]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for TRPM2 Antibody [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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