TRPM7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58525

Novus Biologicals, part of Bio-Techne
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NBP2-58525
NBP2-58525-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TRPM7 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: SQPSCKSHLETGTKDQETVCSKATEGDNTEFGAFVGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAM

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRPM7 Antibody

Immunocytochemistry/ Immunofluorescence: TRPM7 Antibody [NBP2-58525]

Immunocytochemistry/ Immunofluorescence: TRPM7 Antibody [NBP2-58525]

Immunocytochemistry/Immunofluorescence: TRPM7 Antibody [NBP2-58525] - Staining of human cell line U-251 MG shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: TRPM7 Antibody [NBP2-58525]

Immunohistochemistry-Paraffin: TRPM7 Antibody [NBP2-58525]

Immunohistochemistry-Paraffin: TRPM7 Antibody [NBP2-58525] - Staining of human parathyroid gland shows high expression.
Immunohistochemistry-Paraffin: TRPM7 Antibody [NBP2-58525]

Immunohistochemistry-Paraffin: TRPM7 Antibody [NBP2-58525]

Immunohistochemistry-Paraffin: TRPM7 Antibody [NBP2-58525] - Analysis in human parathyroid gland and pancreas tissues using Anti-TRPM7 antibody. Corresponding TRPM7 RNA-seq data are presented for the same tissues.
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Applications for TRPM7 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100. IHC-P, Retrieval method: HIER pH6.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRPM7

The TRPM7 (Transient Receptor Protein-PhosphoLipase C-Interacting Kinase) protein is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. TRPM7, however, is unique among the TRP channel proteins because it is bi-functional. It not only controls ion channels but it also acts as a kinase by phosphorylating proteins.

Alternate Names

CHAK, CHAK1FLJ25718, Channel-kinase 1, EC 2.7.11.1, Long transient receptor potential channel 7, LTRPC ion channel family member 7, LTrpC7, LTrpC-7, LTRPC7FLJ20117, transient receptor potential cation channel subfamily M member 7, transient receptor potential cation channel, subfamily M, member 7, transient receptor potential-phospholipase C-interacting kinase, TRP-PLIK

Gene Symbol

TRPM7

Additional TRPM7 Products

Product Documents for TRPM7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRPM7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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