TRPM8 Antibody [DyLight 550]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-97311R

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Label

DyLight 550 (Excitation = 562 nm, Emission = 576 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRPM8 Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an internal portion of the human TRPM8 protein (between residues 250-300) [UniProt# Q7Z2W7]

Localization

Membrane. Multi-pass membrane protein. Ability to translocate to nucleus.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for TRPM8 Antibody [DyLight 550]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TRPM8

TRPM8 (TRPP8, LTRPC6) is a transient receptor cation channel that has been shown to be a major cold receptor in sensory neurons. TRPM8 has been theorized to be activated by cold temperatures, voltage, calcium store depletion, some lipids, and also the compounds that produce cooling sensations such as menthol or icilin. TRPM8 is aberrantly over-expressed in pancreatic cancer along with colon, lung, breast and skin cancers, and is proposed to be required for cellular proliferation.

Alternate Names

CMR1, LTRPC6, TRPP8

Gene Symbol

TRPM8

Additional TRPM8 Products

Product Documents for TRPM8 Antibody [DyLight 550]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRPM8 Antibody [DyLight 550]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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