Tryptase epsilon/BSSP-4/PRSS22 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13817

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-13817
NBP2-13817-25ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Tryptase epsilon/BSSP-4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: AARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWV

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (80%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tryptase epsilon/BSSP-4/PRSS22 Antibody

Immunocytochemistry/ Immunofluorescence: Tryptase epsilon/BSSP-4/PRSS22 Antibody [NBP2-13817]

Immunocytochemistry/ Immunofluorescence: Tryptase epsilon/BSSP-4/PRSS22 Antibody [NBP2-13817]

Immunocytochemistry/Immunofluorescence: Tryptase epsilon/BSSP-4/PRSS22 Antibody [NBP2-13817] - Staining of human cell line CACO-2 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: Tryptase epsilon/BSSP-4/PRSS22 Antibody [NBP2-13817]

Immunohistochemistry-Paraffin: Tryptase epsilon/BSSP-4/PRSS22 Antibody [NBP2-13817]

Immunohistochemistry-Paraffin: Tryptase epsilon/BSSP-4/PRSS22 Antibody [NBP2-13817] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Applications for Tryptase epsilon/BSSP-4/PRSS22 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tryptase epsilon/BSSP-4

Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase beta-1, also known as mast cell protease 7 (MCPT7), exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. Tryptase epsilon, also known as brain-specific serine protease 4 (BSSP-4) and brain serine protease 2 (BSP-2), is encoded by the PRSS22 gene and preferentially expressed in epithelium-rich tissues such as lung and eye. Tryptase gamma-1, also called transmembrane tryptase, is encoded by TPSG1, one of many serine protease genes clustered on human chromosome 16p13.3.

Alternate Names

BSP-2, BSSP-4, BSSP4, PRSS22

Gene Symbol

PRSS22

Additional Tryptase epsilon/BSSP-4 Products

Product Documents for Tryptase epsilon/BSSP-4/PRSS22 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Tryptase epsilon/BSSP-4/PRSS22 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.