TSEN2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81140

Novus Biologicals, part of Bio-Techne
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NBP1-81140
NBP1-81140-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TSEN2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GCHPTTESFEKSVREDASPLPHVCCCKQDALILQRGLHHEDGSQHIGLLHPGDRGPDHEYVLVEEAECAMSEREAAPNEELVQRNRLICRR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TSEN2 Antibody

Western Blot: TSEN2 Antibody [NBP1-81140]

Western Blot: TSEN2 Antibody [NBP1-81140]

Western Blot: TSEN2 Antibody [NBP1-81140] - Analysis in control (vector only transfected HEK293T lysate) and TSEN2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: TSEN2 Antibody [NBP1-81140]

Immunocytochemistry/ Immunofluorescence: TSEN2 Antibody [NBP1-81140]

Immunocytochemistry/Immunofluorescence: TSEN2 Antibody [NBP1-81140] - Staining of human cell line A-431 shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: TSEN2 Antibody [NBP1-81140]

Immunohistochemistry-Paraffin: TSEN2 Antibody [NBP1-81140]

Immunohistochemistry-Paraffin: TSEN2 Antibody [NBP1-81140] - Staining of human cerebellum shows nuclear positivity in Purkinje cells.

Applications for TSEN2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TSEN2

tRNA splicing is a fundamental process required for cell growth and division. SEN2 is a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns, the first step in tRNA splicing (Paushkin et al., 2004 [PubMed 15109492]).[supplied by OMIM]

Alternate Names

EC 3.1.27.9, HsSen2, MGC2776, PCH2B, SEN2L, SEN2MGC4440, tRNA splicing endonuclease 2 homolog (S. cerevisiae), tRNA splicing endonuclease 2 homolog (SEN2, S. cerevisiae), tRNA-intron endonuclease Sen2, tRNA-splicing endonuclease subunit Sen2

Entrez Gene IDs

80746 (Human)

Gene Symbol

TSEN2

Additional TSEN2 Products

Product Documents for TSEN2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TSEN2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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