TSH alpha/beta Antibody (28.1G11)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11644

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 28.1G11

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TSH alpha/beta Heterodimer Antibodies »

Product Specifications

Immunogen

Human thyroid stimulating hormone

Specificity

Mouse anti Human thyroid stimulating hormone, clone 28.1G11 recognizes human thyroid-stimulating hormone (TSH), a ~28 kDa pituitary hormone which stimulates thyroid growth and the production of thyroid hormone.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for TSH alpha/beta Antibody (28.1G11)

ELISA: TSH alpha/beta Antibody (28.1G11) [NBP3-11644]

ELISA: TSH alpha/beta Antibody (28.1G11) [NBP3-11644]

ELISA: TSH alpha/beta Antibody (28.1G11) [NBP3-11644] - Human thyroid stimulating hormone probed with Mouse anti Human TSH followed by HRP conjugated Rabbit F(ab')2 anti Mouse IgG.

Applications for TSH alpha/beta Antibody (28.1G11)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TSH alpha/beta Heterodimer

TSH (thyroid stimulating hormone), also known as thyrotropin, is a member of the cystine knot growth factor superfamily. It is a heterodimer of a 15 kDa unique subunit, TSH beta, with a 14 kDa alpha subunit, CGa (common glycoprotein hormone alpha) that is shared with lutropin (LH), follitropin (FSH) and chorionic gonadotropin (CG). Production of TSH by the anterior pituitary gland is stimulated by the hypothalamic peptide TRH, and inhibited by feedback from the thyroid hormones triiodothyronine (T3) and thyroxine (T4). Studies in the mouse identify bone marrow as a secondary site of TSH production.

Long Name

Thyroid Stimulating Hormone

Alternate Names

Thyrotropin

Gene Symbol

TSHB

Additional TSH alpha/beta Heterodimer Products

Product Documents for TSH alpha/beta Antibody (28.1G11)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TSH alpha/beta Antibody (28.1G11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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