TSLPR/CRLF2 Antibody (59N5G4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27331

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 59N5G4

Concentration

0.5 mg/ml

View all TSLPR Antibodies »

Product Summary for TSLPR/CRLF2 Antibody (59N5G4)

Immunogen

Amino acids 119-231 of human TSLPR protein were used as the immunogen for the antibody.

Specificity

TSLPR is a glycoprotein with two major isoforms of 359 amino acids and 255 amino acids. In western blotting, bands may be visualized between 27 kD and ~50 kD.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for TSLPR/CRLF2 Antibody (59N5G4)

Western Blot: TSLPR/CRLF2 Antibody (59N5G4) [NBP2-27331]

Western Blot: TSLPR/CRLF2 Antibody (59N5G4) [NBP2-27331]

Western Blot: TSLP R/CRLF2 Antibody (59N5G4) [NBP2-27331] - Analysis of CRLF2 in an A) partial recombinant protein (0.1 ug/ml), B) human muscle and C) liver lysate (5 ug/ml) using CRLF2 antibody.
Immunohistochemistry-Paraffin: TSLPR/CRLF2 Antibody (59N5G4) [NBP2-27331]

Immunohistochemistry-Paraffin: TSLPR/CRLF2 Antibody (59N5G4) [NBP2-27331]

Immunohistochemistry-Paraffin: TSLP R/CRLF2 Antibody (59N5G4) [NBP2-27331] - Formalin-fixed, paraffin-embedded normal human kidney tissue stained with TSLPR antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen.

Applications for TSLPR/CRLF2 Antibody (59N5G4)

Application
Recommended Usage

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TSLPR

TSLPR is a member of the hematopoietin receptor family which acts as a receptor for the cytokine thymic stromal lymphopoietin (TSLP) that promotes CD4(+) T cell homeostasis and contributes to allergic and inflammatory responses. TSLPR is a heterodimeric complex, consisting of the IL-7R-alpha chain and a common gamma-like receptor chain. The protein contains two fibronectin type III-like domains, four conserved cysteine residues, and a WSXWS box-like motif at its N-terminal, while the C-terminal intracellular region contains box 1 and box 2-like motifs. The protein is usually expressed in liver, kidney, heart, and skeletal muscle. The gene for human TSLPR is localized to the pseudoautosomal region, Xp22.3 and Yp11.3.

Long Name

Thymic Stromal Lymphopoietin Receptor

Alternate Names

CRL2, CRLF2, CRLM-2, PCOR1, TSLP R

Gene Symbol

CRLF2

UniProt

Q9HC73

Additional TSLPR Products

Product Documents for TSLPR/CRLF2 Antibody (59N5G4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TSLPR/CRLF2 Antibody (59N5G4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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