TTL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-54787

Novus Biologicals, part of Bio-Techne
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NBP1-54787
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all TTL Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to TTL(tubulin tyrosine ligase) The peptide sequence was selected from the middle region of TTL. Peptide sequence LYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFF. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for TTL Antibody

Western Blot: TTL Antibody [NBP1-54787]

Western Blot: TTL Antibody [NBP1-54787]

Western Blot: TTL Antibody [NBP1-54787] - Titration: 0.2-1 ug/ml, Positive Control: Human Lung.

Applications for TTL Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TTL

TTL catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM].

Alternate Names

EC 6.3.2.25,2410003M22Rik, MGC46235, tubulin tyrosine ligase, tubulin-tyrosine ligase, tubulin--tyrosine ligase

Gene Symbol

TTL

UniProt

Q8NG68 (Human)

Additional TTL Products

Product Documents for TTL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TTL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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