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TULA/STS-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20763

Novus Biologicals, part of Bio-Techne
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NBP2-20763

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human TULA/STS-2. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Bovine (87%).

Localization

Cytoplasm; Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

74 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TULA/STS-2 Antibody

Western Blot: TULA/STS-2 Antibody [NBP2-20763]

Western Blot: TULA/STS-2 Antibody [NBP2-20763]

Western Blot: TULA/STS-2 Antibody [NBP2-20763] - Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE gel, diluted at 1:2000.
Immunocytochemistry/ Immunofluorescence: TULA/STS-2 Antibody [NBP2-20763]

Immunocytochemistry/ Immunofluorescence: TULA/STS-2 Antibody [NBP2-20763]

Immunocytochemistry/Immunofluorescence: TULA/STS-2 Antibody [NBP2-20763] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: TULA/STS-2 Antibody [NBP2-20763]

Immunohistochemistry-Paraffin: TULA/STS-2 Antibody [NBP2-20763]

Immunohistochemistry-Paraffin: TULA/STS-2 Antibody [NBP2-20763] - BT474 xenograft, using UBASH3A antibody at 1:100 dilution. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

Applications for TULA/STS-2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TULA/STS-2

UBASH3A, ubiquitin associated and SH3 domain containing, A, interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface (referenced from Swiss Prot).

Alternate Names

Cbl-interacting protein 4, gene similar to UBA containing SH3 domain10CLIP4STS-2T-cell ubiquitin ligand protein, STS2, Suppressor of T-cell receptor signaling 2, T-cell ubiquitin ligand, TULAubiquitin-associated and SH3 domain-containing protein A, ubiquitin associated and SH3 domain containing A

Gene Symbol

UBASH3A

UniProt

Additional TULA/STS-2 Products

Product Documents for TULA/STS-2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TULA/STS-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.