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TULP3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86897

Novus Biologicals, part of Bio-Techne
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NBP1-86897

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for TULP3 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TGTSGSATAAQPADNLLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARKRKKSKTANYLISIDPVDLSREGESYVGK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TULP3 Antibody

Western Blot: TULP3 Antibody [NBP1-86897]

Western Blot: TULP3 Antibody [NBP1-86897]

Western Blot: TULP3 Antibody [NBP1-86897] - Analysis in control (vector only transfected HEK293T lysate) and TULP3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: TULP3 Antibody [NBP1-86897]

Immunohistochemistry-Paraffin: TULP3 Antibody [NBP1-86897]

Immunohistochemistry-Paraffin: TULP3 Antibody [NBP1-86897] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.

Applications for TULP3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TULP3

This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternate Names

MGC45295, tubby like protein 3, tubby-related protein 3, TUBL3Tubby-like protein 3

Gene Symbol

TULP3

Additional TULP3 Products

Product Documents for TULP3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TULP3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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