TXNDC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80724

Novus Biologicals, part of Bio-Techne
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NBP1-80724
NBP1-80724-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Frozen, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TXNDC2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KELGMESVKAGASGKPEMRLGTQEETSEGDANESSLLVLSSNVPLLALEFLEIAQAKEKAFLPMVSHTFHMRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQP

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23435261)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TXNDC2 Antibody

Immunohistochemistry-Paraffin: TXNDC2 Antibody [NBP1-80724]

Immunohistochemistry-Paraffin: TXNDC2 Antibody [NBP1-80724]

Immunohistochemistry-Paraffin: TXNDC2 Antibody [NBP1-80724] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: TXNDC2 Antibody [NBP1-80724]

Immunohistochemistry-Paraffin: TXNDC2 Antibody [NBP1-80724]

Immunohistochemistry-Paraffin: TXNDC2 Antibody [NBP1-80724] - Staining of human endometrium shows low expression as expected.
Immunohistochemistry-Paraffin: TXNDC2 Antibody [NBP1-80724]

Immunohistochemistry-Paraffin: TXNDC2 Antibody [NBP1-80724]

Immunohistochemistry-Paraffin: TXNDC2 Antibody [NBP1-80724] - Staining in human testis and endometrium tissues using anti-TXNDC2 antibody. Corresponding TXNDC2 RNA-seq data are presented for the same tissues.

Applications for TXNDC2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
Use in WB reported in scientific literature (PMID:33603952) For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TXNDC2

Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS)assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required torectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfidebonds in vitro in the presence of NADP and thioredoxin reductase

Alternate Names

DKFZp434H0311, MGC35026, spermatid-specific thioredoxin-1, SPTRX, SPTRX1, thioredoxin domain containing 2 (spermatozoa), thioredoxin domain-containing 2 (spermatozoa), thioredoxin domain-containing protein 2

Entrez Gene IDs

84203 (Human)

Gene Symbol

TXNDC2

UniProt

Q86VQ3 (Human)

Additional TXNDC2 Products

Product Documents for TXNDC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TXNDC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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