TXNRD2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86919

Novus Biologicals, part of Bio-Techne
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NBP1-86919
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Thioredoxin Reductase 2/TRXR2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: CAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPTAIMAGRLLVQRLF

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (80%). Reactivity reported in scientific literature (PMID: 21813593)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TXNRD2 Antibody

Western Blot: TXNRD2 Antibody [NBP1-86919]

Western Blot: TXNRD2 Antibody [NBP1-86919]

Western Blot: TXNRD2 Antibody [NBP1-86919] - Analysis in human cell line K562.
Immunohistochemistry-Paraffin: TXNRD2 Antibody [NBP1-86919]

Immunohistochemistry-Paraffin: TXNRD2 Antibody [NBP1-86919]

Immunohistochemistry-Paraffin: TXNRD2 Antibody [NBP1-86919] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells.

Applications for TXNRD2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thioredoxin Reductase 2/TRXR2

Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22. (provided by RefSeq)

Alternate Names

SelZ, TR-beta, TRXR2, TXNRD2

Gene Symbol

TXNRD2

Additional Thioredoxin Reductase 2/TRXR2 Products

Product Documents for TXNRD2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TXNRD2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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