Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (94%), Porcine (94%). Backed by our 100% Guarantee.

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TYW3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide near the center of human TYW3. The immunogen is located within amino acids 160 - 210 of TYW3. Amino Acid Squence: ANQKMEENKKRIERFYN

Specificity

TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist; this antibody will detect both isoforms.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TYW3 Antibody - BSA Free

Western Blot: TYW3 AntibodyBSA Free [NBP1-76584]

Western Blot: TYW3 AntibodyBSA Free [NBP1-76584]

Western Blot: TYW3 Antibody [NBP1-76584] - Western blot analysis of TYW3 in A549 cell lysate with TYW3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Applications for TYW3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: TYW3

TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.

Alternate Names

C1orf171, chromosome 1 open reading frame 171, EC 2.1.1, EC 2.1.1.-, FLJ40918, tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW synthesizing protein 3 homolog (S. cerevisiae), tRNA-yW-synthesizing protein 3

Gene Symbol

TYW3

UniProt

Q6IPR3 (Human)

Additional TYW3 Products

Product Documents for TYW3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TYW3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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