UBE2Q2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-49694

Novus Biologicals, part of Bio-Techne
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NBP1-49694
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Rabbit (100%). Backed by our 100% Guarantee.

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all UBE2Q2 Antibodies »

Product Specifications

Immunogen

The immunogen for this product maps to a region between residue 325 and 375 of human Ubiquitin-Conjugating Enzyme E2Q Family Member 2 using the numbering given in entry NP_775740.1 (GeneID 92912).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for UBE2Q2 Antibody

Western Blot: UBE2Q2 Antibody [NBP1-49694]

Western Blot: UBE2Q2 Antibody [NBP1-49694]

Western Blot: UBE2Q2 Antibody [NBP1-49694] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg) and mouse NIH3T3 (M; 50 mcg) cells. Affinity purified rabbit anti-UBE2Q2 antibody used for WB at 0.04 mcg/ml (A) and 0.4 mcg/ml (B) and used for IP at 3 mcg/mg lysate.

Applications for UBE2Q2 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: UBE2Q2

The ubiquitination pathway is known to regulate critical control points in multiple cellular processes by targeting proteins for activation, degradation, or localization at specific intracellular sites. The pathway involves an enzymatic cascade in which the first step activates ubiquitin by forming a high energy thiolester intermediate to ubiquitin activating enzyme (E1) that is subsequently transferred to members of an E2 ubiquitin conjugating enzyme superfamily. The E2 ubiquitin conjugating 45 enzymes function together with a larger superfamily of E3 ubiquitin ligases to transfer activated ubiquitin to specific cellular proteins. The existence of E2 and E3 superfamilies reflects the specificity of each E2-E3 cognate pair for a specific group of cellular substrates. UBE2Q2 is a potentially unique member of the ubiquitin conjugating enzyme superfamily that includes at least 17 phenotypically different subfamilies, many of which contain isozymes. Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).

Long Name

Ubiquitin-conjugating Enzyme E2Q 2

Alternate Names

DKFZp762C143, EC 6.3.2.19, LOC92912, Ubiquitin carrier protein Q2, ubiquitin-conjugating enzyme E2 Q2, ubiquitin-conjugating enzyme E2Q (putative) 2, ubiquitin-conjugating enzyme E2Q family member 2, Ubiquitin-protein ligase Q2

Gene Symbol

UBE2Q2

Additional UBE2Q2 Products

Product Documents for UBE2Q2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for UBE2Q2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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