Ubiquilin 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-56536

Novus Biologicals, part of Bio-Techne
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NBP1-56536
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Ubiquilin 1 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to UBQLN1(ubiquilin 1) The peptide sequence was selected from the middle region of UBQLN1. Peptide sequence QFGGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTA. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

62 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Ubiquilin 1 Antibody

Western Blot: Ubiquilin 1 Antibody [NBP1-56536]

Western Blot: Ubiquilin 1 Antibody [NBP1-56536]

Western Blot: Ubiquilin 1 Antibody [NBP1-56536] - 293T tissue lysate at a concentration of 1ug/ml.
Immunohistochemistry-Paraffin: Ubiquilin 1 Antibody [NBP1-56536]

Immunohistochemistry-Paraffin: Ubiquilin 1 Antibody [NBP1-56536]

Immunohistochemistry-Paraffin: Ubiquilin 1 Antibody [NBP1-56536] - Human Lung, respiratory epethelium, 5.0ug/ml.
Immunohistochemistry-Paraffin: Ubiquilin 1 Antibody [NBP1-56536]

Immunohistochemistry-Paraffin: Ubiquilin 1 Antibody [NBP1-56536]

Immunohistochemistry-Paraffin: Ubiquilin 1 Antibody [NBP1-56536] - Human Lung.
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Applications for Ubiquilin 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Ubiquilin 1

UBQLN1 is an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

Alternate Names

DA41, PLIC-1, UBQLN1, UBQN, XDRP1

Gene Symbol

UBQLN1

UniProt

Q5T6J9 (Human)

Additional Ubiquilin 1 Products

Product Documents for Ubiquilin 1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Ubiquilin 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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