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Uev1a/UBE2V1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58322

Novus Biologicals, part of Bio-Techne
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NBP2-58322
NBP2-58322-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: VLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Uev1a/UBE2V1 Antibody

Immunocytochemistry/ Immunofluorescence: Uev1a/UBE2V1 Antibody [NBP2-58322]

Immunocytochemistry/ Immunofluorescence: Uev1a/UBE2V1 Antibody [NBP2-58322]

Immunocytochemistry/Immunofluorescence: Uev1a/UBE2V1 Antibody [NBP2-58322] - Staining of human cell line Hep G2 shows localization to nucleoplasm.

Applications for Uev1a/UBE2V1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Uev1a/UBE2V1

Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Alternate Names

CIR1, CROC1, UBE2V1

Gene Symbol

UBE2V1

Additional Uev1a/UBE2V1 Products

Product Documents for Uev1a/UBE2V1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Uev1a/UBE2V1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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