UGT1A3 Antibody (1C10)

Novus Biologicals, part of Bio-Techne | Catalog # H00054659-M02

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Validated:

ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 1C10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all UGT1A3 Antibodies »

Product Specifications

Immunogen

UGT1A3 (NP_061966, 30 a.a. ~ 129 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KVLVVPIDGSHWLSMREVLRELHARGHQAVVLTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNMSLVYHRSCV

Specificity

UGT1A3 (1C10)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for UGT1A3 Antibody (1C10)

ELISA: UGT1A3 Antibody (1C10) [H00054659-M02]

ELISA: UGT1A3 Antibody (1C10) [H00054659-M02]

ELISA: UGT1A3 Antibody (1C10) [H00054659-M02] - Detection limit for recombinant GST tagged UGT1A3 is 1 ng/ml as a capture antibody.

Applications for UGT1A3 Antibody (1C10)

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:500
Application Notes
Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: UGT1A3

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene.

Alternate Names

GNT1, UDP glucuronosyltransferase 1 family, polypeptide A3, UDP glucuronosyltransferase 1A3, UDP glycosyltransferase 1 family, polypeptide A3, UDP-glucuronosyltransferase 1-3, UDP-glucuronosyltransferase 1A3, UDP-glucuronosyltransferase 1-C, UDPGT, UDPGT 1-3, UGT1, UGT1*3, UGT1.3, UGT1-03, UGT-1C, UGT1CEC 2.4.1.17

Entrez Gene IDs

54659 (Human)

Gene Symbol

UGT1A3

OMIM

606428 (Human)

UniProt

NP_061966 (Human)

Additional UGT1A3 Products

Product Documents for UGT1A3 Antibody (1C10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for UGT1A3 Antibody (1C10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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